Research Articles
The Molecular Switch: Cloning and Studying Tomato's SIZ1 Gene for Climate-Resilient Crops
Discover how scientists are cloning and studying tomato's SIZ1 gene to develop climate-resilient crops through SUMOylation mechanisms.
The Cellular Tug-of-War: How a Brain Cell Protein Dodges Cancer-Fighting Bullets
Discover how Olig2 SUMOylation protects cells from genotoxic damage by antagonizing p53 gene targeting in this engaging scientific exploration.
The Molecular Dance of a Broken Heart: How Tiny Chemical Tags Transform Cardiac Function
Discover how phosphorylation and SUMOylation of cardiac troponin I regulate heart function and contribute to heart failure pathology.
The Healing Spark: How a Plant Molecule Could Revolutionize Diabetic Wound Care
Discover how Astragaloside IV, a compound from Astragalus root, activates the SUMOylation pathway to promote angiogenesis and healing in diabetic wounds.
SENP1: The Molecular Master Switch in Cancer and a Promising New Therapeutic Target
Explore SENP1's role in cancer development, its molecular mechanisms, and promising therapeutic targeting strategies in this comprehensive scientific overview.
Stopping a Chain Reaction: How Preventing SOD1 Modification Could Combat ALS
Discover how preventing SUMOylation at lysine 75 could inhibit mutant SOD1 aggregation in ALS, offering new therapeutic approaches for this neurodegenerative disease.
Cellular Traffic Control: The Surprising Partnership That Determines Fate in Cystic Fibrosis
Discover how the cross-talk between ubiquitylation and SUMOylation pathways determines CFTR protein fate in cystic fibrosis and leads to innovative treatments.
The Molecular Scissors Fueling Esophageal Cancer: How SENP5 Hijacks Cellular Machinery to Drive Tumor Growth
Discover how SENP5 promotes esophageal squamous cell carcinoma growth through the NF-κB-SLC1A3 axis and its potential as a therapeutic target.